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Eine 1993 publizierte, placebokontrollierte Studie belegte bei 90 alkoholabhängigen Patienten in der Behandlung von Angst und Depression die Ebenbürtigkeit des GABA-B-Agonisten Baclofen gegenüber Diazepam und Amitriptylin, ohne deren Nebenwirkungen aufzuweisen und folgerte, weitere Forschung zu GABA-B-Rezeptorliganden zur Behandlung der Alkoholabhängigkeit sei vielversprechend.

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The regimen was designed to destroy the patients defective autoreactive immune system and replace it with their own blood stem cells that had been removed and treated to eliminate selfreacting lymphocytes.

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